Breast RNA
Mammary epithelial cells (MEpiC) lie within the alveolar lumen of the breast lobules, which together with mammary ducts and adipose tissues, form a complex network in the mammary gland. MEpiC respond to various growth factors and hormonal cues and undergo changes in growth, invasion, and differentiation during pre- and postnatal stages, puberty, and pregnancy. Aberrant levels of hormones and extracellular matrix composition, and other genetic factors have been shown to induce uncontrolled proliferation of MEpiC, resulting in breast cancer development. Understanding the cellular properties of MEpiC will help identify the disease mechanisms in breast cancer and the new targets for therapeutic development.
Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. Mammary fibroblasts (MF) synthesize components of the stromal extracellular matrix of the mammary gland. More importantly, such stromal extracellular matrix regulates the proliferation and differentiation of mammary epithelial cells by influencing their gene expression. In addition, previous studies have shown that mammary fibroblasts play a role in recruiting macrophages for immune surveillance which, in concert with extracellular matrix turnover and angiogenesis, is associated with a supportive mammary microenvironment for tumor cell progression. These results suggest that MF play a stimulatory functional role in breast cancer development and invasion.
Frequently Asked Questions (FAQ)
Where can I find breast products on the Quimigen website?
breast products are available in this section and can be sorted by product families or sub-categories, such as Breast adenocarcinoma RNA, Normal Breast RNA, Breast tumor RNA. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.
What types of products are available in the breast category?
The breast category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The Breast adenocarcinoma RNA, Breast tumor RNA, Normal Breast RNA sub-categories allow you to find the products that meet your needs more quickly.
How can I quickly find a breast product?
To find a breast product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.
Does Quimigen stock several product codes in the breast category?
Yes, Quimigen distributes several product references in the breast category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.
Can I request a quote for breast products?
Yes, you can request a quote for breast products from the product page or by contacting Quimigen (info@quimigen.pt). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.
How can I find out if a breast product is available to order?
The availability of a breast product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Quimigen with the product code or name of the product you are looking for.
What should I do if I cannot find the breast product I am looking for?
If the breast product you are looking for does not appear in the catalogue, please contact Quimigen with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.
Are all breast products available under the same terms and conditions?
No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.