MALTOTETRAOSE [34612-38-9]

Referência NB-64-30186-25mg

Tamanho : 25mg

Marca : Neo Biotech

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MALTOTETRAOSE (Synonyms: α-1,4-Tetraglucose, Fujioligo 450, Amylotetraose)

Catalog No. T5785 Copy Product Info
Purity: 99.87%
Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.

MALTOTETRAOSE

Copy Product Info
Synonyms α-1,4-Tetraglucose, Fujioligo 450, Amylotetraose

Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.

MALTOTETRAOSE
Cas No. 34612-38-9
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Purity:99.87%
Color:White
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Product Introduction

Bioactivity
Description
Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.
In vivo
Maltotetraose reduced PDGF-induced sprout formation by mouse aorta explants and inhibited TNF-α-induced NF-κB activation and ICAM-1 expression in MOVAS-1 cells[1].
Animal Research
Ex vivo migration of VSMCs was measured by aortic . Mouse thoracic aortas were excised from 8-week-old male Balb/c mice and adipose tissue was removed. The aortas were sectioned into 1-mm–long cross-sections, rinsed with serum-free DMEM, treated with 1 mg/mL collagenenase type II, placed in matrigel-coated wells, covered with 50 uL matrigel, and allowed to gel for more than 30 min at 37℃ in a 5% CO2 atmosphere. The aortic rings were treated with 20 ug/mL MALTOTETRAOSE for 30 min, followed by stimulation with 20 ng/mL PDGF-BB. Aortic ring sprouts were photographed on day 7[1].
Synonymsα-1,4-Tetraglucose, Fujioligo 450, Amylotetraose
Chemical Properties
Molecular Weight666.58
FormulaC24H42O21
Cas No.34612-38-9
SmilesOC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]4CO)O[C@@H]3CO)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O
Relative Density.1.3922 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (82.51 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5002 mL7.5010 mL15.0020 mL75.0098 mL
5 mM0.3000 mL1.5002 mL3.0004 mL15.0020 mL
10 mM0.1500 mL0.7501 mL1.5002 mL7.5010 mL
20 mM0.0750 mL0.3750 mL0.7501 mL3.7505 mL
50 mM0.0300 mL0.1500 mL0.3000 mL1.5002 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.