Size : 25mg
Phone : +1 850 650 7790
Synonyms: α-1,4-Tetraglucose, Fujioligo 450, Amylotetraose
| Description | Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development. |
| In vivo | Maltotetraose reduced PDGF-induced sprout formation by mouse aorta explants and inhibited TNF-α-induced NF-κB activation and ICAM-1 expression in MOVAS-1 cells[1]. |
| Synonyms | α-1,4-Tetraglucose, Fujioligo 450, Amylotetraose |
| Animal Research | Ex vivo migration of VSMCs was measured by aortic . Mouse thoracic aortas were excised from 8-week-old male Balb/c mice and adipose tissue was removed. The aortas were sectioned into 1-mm–long cross-sections, rinsed with serum-free DMEM, treated with 1 mg/mL collagenenase type II, placed in matrigel-coated wells, covered with 50 uL matrigel, and allowed to gel for more than 30 min at 37℃ in a 5% CO2 atmosphere. The aortic rings were treated with 20 ug/mL MALTOTETRAOSE for 30 min, followed by stimulation with 20 ng/mL PDGF-BB. Aortic ring sprouts were photographed on day 7[1]. |
| Molecular Weight | 666.58 |
| Formula | C24H42O21 |
| Cas No. | 34612-38-9 |
| Smiles | OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]4CO)O[C@@H]3CO)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O |
| Relative Density. | 1.3922 g/cm3 (Estimated) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (82.51 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||||||||||||
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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