TRIM28 Antibody - N-terminal region - FITC
Referencia ARP31460_P050-FITC
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Marca : Aviva Systems Biology
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TRIM28 Antibody - N-terminal region : FITC (ARP31460_P050-FITC)
| Datasheets/Manuals | Printable datasheet for anti-TRIM28 (ARP31460_P050-FITC) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | FITC: Fluorescein Isothiocyanate |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM28 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 92%; Dog: 100%; Human: 100%; Mouse: 93%; Rat: 93% |
| Peptide Sequence | Synthetic peptide located within the following region: AASAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSP |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-TRIM28 (ARP31460_P050-FITC) antibody is Catalog # AAP31460 (Previous Catalog # AAPP24061) |
| Sample Type Confirmation | TRIM28 is supported by BioGPS gene expression data to be expressed in MCF7 |
| Reference | Kamitani,S., (2008) Biochem. Biophys. Res. Commun. 370 (2), 366-370 |
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| Gene Symbol | TRIM28 |
| Gene Full Name | Tripartite motif containing 28 |
| Alias Symbols | KAP1, TF1B, RNF96, TIF1B, PPP1R157 |
| NCBI Gene Id | 10155 |
| Protein Name | Transcription intermediary factor 1-beta |
| Description of Target | TRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING,a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Uniprot ID | Q13263 |
| Protein Accession # | NP_005753 |
| Nucleotide Accession # | NM_005762 |
| Protein Size (# AA) | 835 |
| Molecular Weight | 88kDa |
| Protein Interactions | WWOX; ERLIN2; HUWE1; SUMO1; UBC; SPRTN; SENP7; HAUS2; MAGEC2; CBX5; WHSC1; UBE2I; AURKA; SUMO2; SUMO3; RNF4; CEP250; TRIM28; HIF1A; CHD3; ATM; ZNF350; STAU1; HIST3H3; LYN; NEDD8; MDM2; ZBTB1; RPA3; RPA2; RPA1; RNF2; SUZ12; EZH2; BMI1; EED; BRCC3; WRNIP1; |
