TRIM28 Antibody - N-terminal region - FITC

Referência ARP31460_P050-FITC

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Marca : Aviva Systems Biology

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TRIM28 Antibody - N-terminal region : FITC (ARP31460_P050-FITC)

Datasheets/ManualsPrintable datasheet for anti-TRIM28 (ARP31460_P050-FITC) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationFITC: Fluorescein Isothiocyanate
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human TRIM28
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 92%; Dog: 100%; Human: 100%; Mouse: 93%; Rat: 93%
Peptide SequenceSynthetic peptide located within the following region: AASAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSP
Concentration0.5 mg/ml
Blocking PeptideFor anti-TRIM28 (ARP31460_P050-FITC) antibody is Catalog # AAP31460 (Previous Catalog # AAPP24061)
Sample Type Confirmation

TRIM28 is supported by BioGPS gene expression data to be expressed in MCF7

ReferenceKamitani,S., (2008) Biochem. Biophys. Res. Commun. 370 (2), 366-370
Gene SymbolTRIM28
Gene Full NameTripartite motif containing 28
Alias SymbolsKAP1, TF1B, RNF96, TIF1B, PPP1R157
NCBI Gene Id10155
Protein NameTranscription intermediary factor 1-beta
Description of TargetTRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING,a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDQ13263
Protein Accession #NP_005753
Nucleotide Accession #NM_005762
Protein Size (# AA)835
Molecular Weight88kDa
Protein InteractionsWWOX; ERLIN2; HUWE1; SUMO1; UBC; SPRTN; SENP7; HAUS2; MAGEC2; CBX5; WHSC1; UBE2I; AURKA; SUMO2; SUMO3; RNF4; CEP250; TRIM28; HIF1A; CHD3; ATM; ZNF350; STAU1; HIST3H3; LYN; NEDD8; MDM2; ZBTB1; RPA3; RPA2; RPA1; RNF2; SUZ12; EZH2; BMI1; EED; BRCC3; WRNIP1;