Reagents and instruments for immunology, cell biology and molecular biology.
 
Very-low-density lipoprotein

Very-low-density lipoprotein

Very-low-density lipoprotein (VLDL) is a type of lipoprotein synthesized by the liver, playing a critical role in lipid transport within the bloodstream. As one of the five major classes of lipoproteins, VLDL is primarily responsible for transporting triglycerides, cholesterol, and other lipids to various tissues in the body. 

Structure and Composition

VLDL particles are relatively large, with diameters ranging from 30 to 80 nanometers. They are composed of approximately 90% lipids and 10% proteins, giving them a low density of 0.96 to 1.006 g/ml. The lipid component consists mainly of triglycerides (about 70% of the total mass), along with cholesterol esters and phospholipids. The protein component includes several apolipoproteins, notably apolipoprotein B-100 (apoB-100), which is essential for VLDL metabolism and receptor recognition, as well as apoC-I, apoC-II, apoC-III, and apoE, which play roles in lipid metabolism and transport.

Function of VLDL

The primary function of VLDL is to transport endogenous triglycerides and cholesterol from the liver to peripheral tissues, where they can be utilized for energy or stored. VLDL is crucial for maintaining lipid homeostasis in the body. Once released into the bloodstream, VLDL interacts with lipoprotein lipase (LPL) in capillary beds, where triglycerides are hydrolyzed, allowing fatty acids to enter tissues for energy production or storage. As triglycerides are removed, VLDL is converted into intermediate-density lipoprotein (IDL) and eventually low-density lipoprotein (LDL) as it loses triglyceride content and gains cholesterol.

Frequently Asked Questions (FAQ)

How can I quickly find a vldl product?

To find a vldl product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Quimigen stock several product codes in the vldl category?

Yes, Quimigen distributes several product references in the vldl category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for vldl products?

Yes, you can request a quote for vldl products from the product page or by contacting Quimigen (info@quimigen.pt). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a vldl product is available to order?

The availability of a vldl product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Quimigen with the product code or name of the product you are looking for.

What should I do if I cannot find the vldl product I am looking for?

If the vldl product you are looking for does not appear in the catalogue, please contact Quimigen with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all vldl products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.

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