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> Dopamine hydrochloride [62-31-7]

Dopamine hydrochloride [62-31-7]

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Cat# NB-64-07499-100mg

Size : 100mg

Brand : Neo Biotech

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Phone : +1 850 650 7790

Dopamine hydrochloride (Synonyms: Dopamine HCl, ASL279)

Catalog No. T1644 Copy Product Info
Purity: 99.83%
Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter that mainly acts on dopamine receptors (D1-5 receptors) (EC50=2.7 nM). Dopamine hydrochloride induces VEGFR2 endocytosis through D2 dopamine receptor and has pro-angiogenic activity.

Dopamine hydrochloride

Copy Product Info
Synonyms Dopamine HCl, ASL279

Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter that mainly acts on dopamine receptors (D1-5 receptors) (EC50=2.7 nM). Dopamine hydrochloride induces VEGFR2 endocytosis through D2 dopamine receptor and has pro-angiogenic activity.

Dopamine hydrochloride
Cas No. 62-31-7
Other Forms of Dopamine hydrochloride:
Dopamine hydrochloride (Standard)TMSM-106862-31-7
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Batch Information
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Purity:99.83%
Color:White
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COA LCMS HNMR

Product Introduction
Bioactivity
Description
Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter that mainly acts on dopamine receptors (D1-5 receptors) (EC50=2.7 nM). Dopamine hydrochloride induces VEGFR2 endocytosis through D2 dopamine receptor and has pro-angiogenic activity.
Targets&IC50
Amplitude of GABAA IPSCs:3.4 ± 0.8 μM, Arachidonic acid (Release):0.5 nM (CHO cells), Excitatory postsynaptic currents:12.8 ± 2.8 μM, Prolactin release:60 nM, Dopamine D1 receptor:55.5 nM (EC50)
In vitro
METHODS: CYP3A4/5, CYP2C19 and CYP2C9 were treated with Resmetirom to detect the inhibition of cell growth.
RESULTS: The IC50 of ResmetiromCYP3A4/5 and CYP2C19 were both greater than 50 μM, with no growth inhibitory effect. The inhibitory effect on CYP2C9 was relatively weak, and the IC50 was approximately 22 μM. [1]
SynonymsDopamine HCl, ASL279
Chemical Properties
Molecular Weight189.64
FormulaC8H12ClNO2
Cas No.62-31-7
SmilesCl.NCCc1ccc(O)c(O)c1
Relative Density.1.4 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (290.02 mM), Sonication is recommended.
H2O: 19 mg/mL (100.19 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM5.2731 mL26.3657 mL52.7315 mL263.6575 mL
5 mM1.0546 mL5.2731 mL10.5463 mL52.7315 mL
10 mM0.5273 mL2.6366 mL5.2731 mL26.3657 mL
20 mM0.2637 mL1.3183 mL2.6366 mL13.1829 mL
50 mM0.1055 mL0.5273 mL1.0546 mL5.2731 mL
100 mM0.0527 mL0.2637 mL0.5273 mL2.6366 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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