Sulfo DBCO-PEG4-amine [2055198-05-3]
Cat# NB-64-73578-100mg
Size : 100mg
Brand : Neo Biotech
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Phone : +1 850 650 7790
Sulfo DBCO-PEG4-amine
Catalog No. T16957 Copy Product Info
Sulfo DBCO-PEG4-amine is a PEG-based linker for PROTACs, connecting two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Sulfo DBCO-PEG4-amine
Copy Product InfoSulfo DBCO-PEG4-amine is a PEG-based linker for PROTACs, connecting two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Cas No. 2055198-05-3
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sulfo DBCO-PEG4-amine is a PEG-based linker for PROTACs, connecting two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
| In vitro | PROTACs consist of two distinct ligands linked by a connector: one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins [1]. |
| Molecular Weight | 674.77 |
| Formula | C32H42N4O10S |
| Cas No. | 2055198-05-3 |
| Smiles | NCCOCCOCCOCCOCCC(=O)NCC(C(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12)S(O)(=O)=O |
| Relative Density. | 1.36 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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