U2AF2 Antibody - C-terminal region - HRP
Referência ARP40285_P050-HRP
Tamanho : 100ul
Marca : Aviva Systems Biology
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U2AF2 Antibody - C-terminal region : HRP (ARP40285_P050-HRP)
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| Datasheets/Manuals | Printable datasheet for anti-U2AF2 (ARP40285_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human U2AF2 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGV |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-U2AF2 (ARP40285_P050-HRP) antibody is Catalog # AAP40285 |
| Sample Type Confirmation | There is BioGPS gene expression data showing that U2AF2 is expressed in HepG2 |
| Gene Symbol | U2AF2 |
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| Gene Full Name | U2 small nuclear RNA auxiliary factor 2 |
| Alias Symbols | U2AF65 |
| NCBI Gene Id | 11338 |
| Protein Name | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2, isoform CRA_a EMBL EDL31286.1 |
| Description of Target | U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. |
| Uniprot ID | Q80XR5 |
| Protein Accession # | NP_001012496 |
| Nucleotide Accession # | NM_001012478 |
| Protein Size (# AA) | 471 |
| Molecular Weight | 53kDa |
| Protein Interactions | THAP1; PUF60; U2AF1; SNRPA; AES; DACH1; SUMO3; UBC; SUZ12; EED; TERF1; EZH2; RNF2; PRPF40A; TCERG1; APBB1; PIN1; SH3RF2; SRPK2; SRPK1; SF1; SRSF1; RBM39; QKI; SCAF11; PRPF3; RBM10; RBM4; SMAD5; IL7R; HNRNPK; HNRNPD; HLA-DMA; SUGP1; CCAR1; SAP30BP; RBFOX2; |
