- Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TACR1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human TACR1.
Host
Rabbit
Reactivity
Guinea pig, Human, Rat
Specificity
This antibody is specific to human NK-1.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunohistochemistry (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Immunohistochemistry
Western Blot
- Gene Info — TACR1
Entrez GeneID
6869Gene Name
TACR1
Gene Alias
NK1R, NKIR, SPR, TAC1R
Gene Description
tachykinin receptor 1
Omim ID
162323Gene Ontology
HyperlinkGene Summary
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq
Other Designations
NK-1 receptor|neurokinin 1 receptor|tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
- Interactomes
- Pathways
- Diseases
- Alcoholism
- Anorexia Nervosa
- Asthma
- Bipolar Disorder
- Bulimia
- Chronic Disease
- Constipation
- Cough
- Endometriosis
+ View More Disease
- Publication Reference
- Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection.
Hazlett LD, McClellan SA, Barrett RP, Liu J, Zhang Y, Lighvani S.
Investigative Ophthalmology & Visual Science 2007 Feb; 48(2):797.
Application：IF, Mouse, Peritoneal macrophages.
- Neurokinin-1 receptor activation in Botzinger complex evokes bradypnoea.
Fong AY, Potts JT.
The Journal of Physiology 2006 Sep; 575(Pt 3):869.
Application：IHC, Rat, Rat brain.
- An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice.
Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL 2nd, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL.
The Journal of Pharmacology and Experimental Therapeutics 2006 Oct; 319(1):208.
- Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation.
Lai JP, Ho WZ, Kilpatrick LE, Wang X, Tuluc F, Korchak HM, Douglas SD.
PNAS 2006 May; 103(20):7771.
Application：IF, Human, THP-1 cells.
- Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection.
TACR1 polyclonal antibody
Referência PAB12009
Tamanho : 100uL
Marca : Abnova
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Telefone : +1 850 650 7790