SSB Recombinant Protein
Referência OPCA01872-20UG
Tamanho : 20ug
Marca : Aviva Systems Biology
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SSB Recombinant Protein (Human) (OPCA01872)
| Datasheets/Manuals | Printable datasheet for SSB Recombinant Protein (Human) (OPCA01872) |
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| Predicted Species Reactivity | Homo sapiens|Human |
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| Product Format | Liquid or Lyophilized powder |
| Host | Human |
| Reconstitution and Storage | -20°C or -80°C |
| Purification | Affinity purified using IMAC |
| Concentration | Varies by lot. See vial for exact concentration. |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Peptide Sequence | MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ |
| Protein Sequence | MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ |
| Storage Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| Source | E.coli |
| Protein Range | 1-408 aa |
| Tag | N-terminal 6xHis-SUMO-tagged |
| Reference | Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding.Chan E.K.L., Sullivan K.F., Tan E.M.Nucleic Acids Res. 17:2233-2244(1989) |
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| Gene Symbol | SSB |
| Gene Full Name | small RNA binding exonuclease protection factor La |
| Alias Symbols | autoantigen La, La, la autoantigen, La ribonucleoprotein, La ribonucleoprotein domain family, member 3, La/SSB, LARP3, lupus La antigen, lupus La protein, sjoegren syndrome type B antigen, Sjogren syndrome antigen B, SS-B, SS-B/La protein. |
| NCBI Gene Id | 6741 |
| Protein Name | Lupus La protein |
| Description of Target | Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597). |
| Uniprot ID | P05455 |
| Protein Accession # | NP_001281074.1 |
| Nucleotide Accession # | NM_001294145.1 |
| Protein Size (# AA) | Full Length |
| Molecular Weight | 62.8 kda |
