A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.

Applications:
Suitable for use as a histone deacetylase inhibitor.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Synonyms
Butanoic Acid Sodium Salt; Butyric acid Sodium Salt; Adimix; Butyrate Sodium; Gustor XXI B 70; Sodium Butanoate;

CAS Number:
156-54-7

Molecular Formula:
C₄H₇NaO₂

Molecular Weight:
110.09

Appearance:
Supplied as a white to off-white powder

Purity:
≥99%

Loss on Drying:
≤5%

Melting Point:
251-252ºC

Storage Stability:
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive. Store under inert atmosphere.