Rabbit Anti- VPS33B Polyclonal Antibody

Referência FNab09436

Tamanho : 100ug

Marca : FineTest

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Synonyms:Vacuolar protein sorting-associated protein 33B (hVPS33B)|VPS33B antibody
Catalogue No.:FNab09436Reactivity:Human, Mouse, Rat, Zebrafish
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
Size
100µg Inquiry
Dispatch Time: About 3 working days
Product Name
VPS33B antibody
Catalogue No.
FNab09436
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
vacuolar protein sorting 33 homolog B(yeast)
Alternative Names
Vacuolar protein sorting-associated protein 33B (hVPS33B)|VPS33B antibody
UniProt ID
Q9H267
Observed MW
71 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab09436(VPS33B antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human kidney using FNab09436(VPS33B antibody) at dilution of 1:100
Background
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages(PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity(PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies(MVBs) promoting MVBs maturation in megakaryocytes(By similarity).

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