Quinacrine mustard hydrochloride [4213-45-0]
Referência NB-64-24732-5mg
Tamanho : 5mg
Marca : Neo Biotech
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Quinacrine mustard hydrochloride (Synonyms: Quinacrine mustard HCl)
Catalog No. T37031 Copy Product Info
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography.
Quinacrine mustard hydrochloride
Copy Product InfoSynonyms Quinacrine mustard HCl
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography.
Cas No. 4213-45-0
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography. |
| In vitro | Quinacrine mustard hydrochloride (0.2 μM; 4h) induced cell cycle arrest at G2+M-phase with the accumulation of cells in this compartment by 50% in HL-60 cells.[1] Quinacrine mustard hydrochloride (5 μg/ml) can be used for the DNA strain of plant, animal, or human chromosomes.[2] Quinacrine mustard hydrochloride (28 μM) increases the number of mutants that appeared after exposure to bacteria.[3] |
| Cell Research | Cell experiment: Quinacrine mustard hydrochloride (0.2 μM; 4h) induced cell cycle arrest at the G2+M phase in HL-60 cells and increased the accumulation of cells in this phase by 50%. |
| Synonyms | Quinacrine mustard HCl |
| Molecular Weight | 505.31 |
| Formula | C23H29Cl4N3O |
| Cas No. | 4213-45-0 |
| Smiles | Cl.ClC=1C=CC=2C(=NC=3C=CC(OC)=CC3C2NC(C)CCCN(CCCl)CCCl)C1 |
| Relative Density. | 1.271g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Chloroform: Soluble H2O: Soluble |