Quinacrine analog 34 [1411646-44-0]

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Referência NB-64-23426-10mg

Tamanho : 10mg

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Marca : Neo Biotech

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Contactar o distribuidor local :

Telefone : +1 850 650 7790

Quinacrine analog 34 (Synonyms: Autophagy-IN-4)

Catalog No. T35747 Copy Product Info

Purity: 99.98%

Quinacrine analog 34 is a potent autophagy inhibitor (EC₅₀ = 0.5 μM, LD₅₀ = 27 μM) that upregulates the protein levels of the autophagy marker LC3-II and induces lysosomal deacidification.

Quinacrine analog 34

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Synonyms Autophagy-IN-4

Quinacrine analog 34 is a potent autophagy inhibitor (EC₅₀ = 0.5 μM, LD₅₀ = 27 μM) that upregulates the protein levels of the autophagy marker LC3-II and induces lysosomal deacidification.

Cas No. 1411646-44-0

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Purity:99.98%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Quinacrine analog 34 is a potent autophagy inhibitor (EC₅₀ = 0.5 μM, LD₅₀ = 27 μM) that upregulates the protein levels of the autophagy marker LC3-II and induces lysosomal deacidification.
Targets&IC50	autophagy:2.5 μM (LD₅₀)
Synonyms	Autophagy-IN-4

Chemical Properties

Molecular Weight	358.91
Formula	C₂₀H₂₇ClN₄
Cas No.	1411646-44-0
Smiles	ClC=1C=CC2=C(N=C3C(=C2NCCN4CCN(C)CC4)CCCC3)C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 5 mg/mL (13.93 mM), Sonication is recommended.

DMSO:PBS (pH 7.2) (1:1): < 1?mg/mL?(insoluble), Sonication is recommended.

Ethanol: 2.5 mg/mL (6.97 mM), Sonication is recommended.

DMF: 5 mg/mL (13.93 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.7862 mL	13.9311 mL	27.8621 mL	139.3107 mL
5 mM	0.5572 mL	2.7862 mL	5.5724 mL	27.8621 mL

DMSO/DMF

	1mg	5mg	10mg	50mg
10 mM	0.2786 mL	1.3931 mL	2.7862 mL	13.9311 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.