Quilseconazole [1340593-70-5]
Referência M28201-10mg
Tamanho : 10mg
Marca : AbMole Bioscience
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VT-1129
Quality Control & Documentation
Biological Activity
Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes.
Chemical Information
| Molecular Weight | 513.37 |
| Formula | C22H14F7N5O2 |
| CAS Number | 1340593-70-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Rogelio de J Treviño-Rangel, et al. J Fungi (Basel). Recent Antifungal Pipeline Developments against Candida auris: A Systematic Review