OTX1 Antibody - N-terminal region - FITC

Referência ARP39102_P050-FITC

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Marca : Aviva Systems Biology

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OTX1 Antibody - N-terminal region : FITC (ARP39102_P050-FITC)

Datasheets/ManualsPrintable datasheet for anti-OTX1 (ARP39102_P050-FITC) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationFITC: Fluorescein Isothiocyanate
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human OTX1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: PRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQV
Concentration0.5 mg/ml
Blocking PeptideFor anti-OTX1 (ARP39102_P050-FITC) antibody is Catalog # AAP39102 (Previous Catalog # AAPP21211)
ReferenceHillier,L.W., (2005) Nature 434 (7034), 724-731
Gene SymbolOTX1
Gene Full NameOrthodenticle homeobox 1
Alias SymbolsFLJ38361, MGC15736
NCBI Gene Id5013
Protein NameHomeobox protein OTX1
Description of TargetOTX1 probably plays a role in the development of the brain and the sense organs. OTX1 can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
Uniprot IDP32242
Protein Accession #NP_055377
Nucleotide Accession #NM_014562
Protein Size (# AA)354
Molecular Weight37kDa
Protein InteractionsKRTAP10-3; KRTAP10-8; KRTAP10-5; KRTAP10-11; KRTAP10-1; KRTAP10-9; KRTAP12-2; LCE2D; LCE2A; LCE1B; LCE4A; MGAT5B; KRTAP3-3; KRTAP4-2; KRTAP4-7; KRTAP9-4; KRTAP9-2; KRTAP4-11; GEMIN8P4; KRTAP5-6; KRTAP26-1; KRTAP12-4; KRTAP3-2; KCNK16; KRTAP4-12; RGS17; RB