MYST2 Antibody - N-terminal region - FITC
Referência ARP31518_P050-FITC
Tamanho : 100ul
Marca : Aviva Systems Biology
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MYST2 Antibody - N-terminal region : FITC (ARP31518_P050-FITC)
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| Datasheets/Manuals | Printable datasheet for anti-KAT7 (ARP31518_P050-FITC) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | FITC: Fluorescein Isothiocyanate |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human MYST2 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLS |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-KAT7 (ARP31518_P050-FITC) antibody is Catalog # AAP31518 (Previous Catalog # AAPP24087) |
| Reference | Wu,Z.Q. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (6), 1919-1924 |
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| Gene Symbol | KAT7 |
| Gene Full Name | K(lysine) acetyltransferase 7 |
| Alias Symbols | HBO1, HBOA, MYST2, ZC2HC7 |
| NCBI Gene Id | 11143 |
| Protein Name | Histone acetyltransferase KAT7 |
| Description of Target | MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly. |
| Uniprot ID | O95251 |
| Protein Accession # | NP_008998 |
| Nucleotide Accession # | NM_007067 |
| Protein Size (# AA) | 611 |
| Molecular Weight | 71kDa |
| Protein Interactions | UBC; RNF2; EZH2; VIM; CDK11B; APP; HAP1; BARD1; LRIF1; ING4; JADE1; CSNK1E; DYNC1I1; CDT1; tat; HIST1H4A; HIST1H3A; HIST2H2AC; GMNN; ORC2; MCM2; CDC6; JUN; KIAA1377; CEP70; CBX8; CAAP1; KCTD13; PPID; WDR33; NINL; ZBTB8B; HOOK2; KATNBL1; POLB; CALCOCO2; AT |
