Mouse CD81C Antibody : APC
Referência OASB02294
Tamanho : 0.1mg
Marca : Aviva Systems Biology
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Mouse CD81C Antibody : APC (OASB02294)
| Datasheets/Manuals | Printable datasheet for Mouse CD81C Antibody : APC (OASB02294) |
|---|
| Tested Species Reactivity | Mouse |
|---|---|
| Predicted Species Reactivity | Mouse |
| Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Host | Hamster |
| Conjugation | APC |
| Application | FC |
| Additional Information | Description: CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gamma/delta+ T cells to more mature T cells with alpha/beta T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR beta chain and glycoprotein pTalpha. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro. |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Mouse epithelial cell line PAM212 |
| Concentration | 0.1 mg/mL |
| Specificity | CD81 |
| Gene Symbol | CD81 |
|---|---|
| Gene Full Name | CD81 antigen |
| Alias Symbols | Ta, Tap, Tsp, Tapa1, Tapa-1, Tspan28 |
| NCBI Gene Id | 12520 |
| Protein Name | CD81 antigen |
| Uniprot ID | P35762 |
| Protein Accession # | NP_598416.1 |
| Nucleotide Accession # | NM_133655.2 |
