ESR2 Antibody - N-terminal region - FITC
Referência ARP31652_P050-FITC
Tamanho : 100ul
Marca : Aviva Systems Biology
Contactar o distribuidor local :
Telefone : +1 850 650 7790
ESR2 Antibody - N-terminal region : FITC (ARP31652_P050-FITC)
| Datasheets/Manuals | Printable datasheet for anti-ESR2 (ARP31652_P050-FITC) antibody |
|---|
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep |
|---|---|
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | FITC: Fluorescein Isothiocyanate |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human ESR2 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 85%; Rat: 100%; Sheep: 93% |
| Peptide Sequence | Synthetic peptide located within the following region: TPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGN |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-ESR2 (ARP31652_P050-FITC) antibody is Catalog # AAP31652 (Previous Catalog # AAPP02439) |
| Sample Type Confirmation | There is BioGPS gene expression data showing that ESR2 is expressed in HepG2 |
| Specificity | Directed towards isoforms 1-8. |
| Reference | Rothwarf,D.M., et al., (2006) J. Endocrinol. Invest. 29 (1), 5-10 |
|---|---|
| Gene Symbol | ESR2 |
| Gene Full Name | Estrogen receptor 2 (ER beta) |
| Alias Symbols | Erb, ESRB, ODG8, ESTRB, NR3A2, ER-BETA, ESR-BETA |
| NCBI Gene Id | 2100 |
| Protein Name | Estrogen receptor beta |
| Description of Target | ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |
| Uniprot ID | Q92731 |
| Protein Accession # | NP_001428 |
| Nucleotide Accession # | NM_001437 |
| Protein Size (# AA) | 530 |
| Molecular Weight | 59kDa |
| Protein Interactions | PLSCR1; MEOX2; NOTCH2NL; RFX6; MMS19; BCAS2; NCOA1; RPS18; MRPS15; MRPS22; ZC3HAV1; PTCD3; EXOSC4; MRPS2; MED4; MRPS27; MRPS31; MED17; TRIM24; NRIP1; NCOA3; STAU1; SP1; PABPC5; MYLK2; RPS11; RPS4X; RPLP0; RPL36AL; PPP5C; HSPA8; ESR2; ESR1; ACTB; SRA1; ARI |
