- Specifications
Product Description
Mouse recombinant monoclonal antibody raised against human EGFR.
Antibody Species
Mouse
Immunogen
Original antibody is raised against partially purified EGFR from A431 cells.
Reactivity
Human
Form
Liquid
Preparation Method
Mammalian cell (HEK293) expression system
Isotype
IgG2a kappa
Recommend Usage
Flow Cytometry
Immunofluorescence
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
Neutralization
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. - Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunofluorescence
Flow Cytometry
Immunoprecipitation
Western Blot
Neutralization
- Gene Info — EGFR
Entrez GeneID
1956Gene Name
EGFR
Gene Alias
ERBB, ERBB1, HER1, PIG61, mENA
Gene Description
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
Other Designations
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor
- Interactomes
- Pathways
- Diseases
EGFR recombinant monoclonal antibody, clone 528
Referência RAB03425
Tamanho : 200ug
Marca : Abnova
Contactar o distribuidor local :
Telefone : +1 850 650 7790