DAZ2 Antibody - N-terminal region - HRP

Referência ARP40250_P050-HRP

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Marca : Aviva Systems Biology

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DAZ2 Antibody - N-terminal region : HRP (ARP40250_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-DAZ2 (ARP40250_P050-HRP) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationIHC, WB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human DAZ2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
Peptide SequenceSynthetic peptide located within the following region: MDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQ
Concentration0.5 mg/ml
Blocking PeptideFor anti-DAZ2 (ARP40250_P050-HRP) antibody is Catalog # AAP40250 (Previous Catalog # AAPS02809)
Sample Type Confirmation

DAZ2 is strongly supported by BioGPS gene expression data to be expressed in Daudi

ReferenceKuo,P.L., (2004) Fertil. Steril. 81 (4), 1034-1040
Gene SymbolDAZ2
Gene Full NameDeleted in azoospermia 2
Alias SymbolspDP1678
NCBI Gene Id57055
Protein NameDeleted in azoospermia protein 2
Description of TargetDAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Uniprot IDQ2KHN6
Protein Accession #NP_001005785
Nucleotide Accession #NM_001005785
Protein Size (# AA)534
Molecular Weight59kDa
Protein InteractionsUBC; PUM2;