Chondroitin sulfate (sodium) (from bovine) [9082-07-9]

Referência HY-B2162B-5g

Tamanho : 5g

Marca : MedChemExpress

Contactar o distribuidor local :


Telefone : +1 850 650 7790

Description

Chondroitin sulfate (Chondroitin polysulfate) sodium (from bovine)) is a sulfated linear polysaccharide extracted from bovine sources, belonging to glycosaminoglycans. Chondroitin sulfate sodium (from bovine) inhibits osteoclast-mediated bone resorption and exhibits antioxidant activity, which is negatively correlated with molecular weight. Chondroitin sulfate sodium (from bovine) can be used in studies related to osteoarthritis[1][2].

In Vitro

Chondroitin sulfate sodium (from bovine) (1-1000 μg/mL; 7 days) reduces the formation of TRAP-positive multinucleated osteoclasts derived from human peripheral blood mononuclear cells only at the concentration of 1000 μg/mL[1].
Chondroitin sulfate sodium (from bovine) (1-1000 μg/mL; 10 days) potently and persistently inhibits the bone resorptive activity of osteoclasts derived from human peripheral blood mononuclear cells[1].
Chondroitin sulfate sodium (from bovine) exhibits concentration-dependent in vitro antioxidant activity. Among these fractions, the lowest molecular weight component (BCS-II-4, 19.7 kDa) shows the strongest scavenging activity against superoxide anions, DPPH radicals and hydroxyl radicals, as well as the highest ferric ion reducing power[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Solvant et solubilité
In Vitro: 

H2O : 40 mg/mL (Need ultrasonic)

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureté et documentation
Références