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> Chemokine Receptor D6 (ACKR2) (NM_001296) Human Recombinant Protein

Chemokine Receptor D6 (ACKR2) (NM_001296) Human Recombinant Protein

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Referência TP302459

Tamanho : 20ug

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Chemokine Receptor D6 (ACKR2) (NM_001296) Human Recombinant Protein

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SKU
TP302459
Recombinant protein of human chemokine binding protein 2 (CCBP2), 20 µg
 

Other products for "Chemokine Receptor D6 or NM_001296"

Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC202459 protein sequence
Red=Cloning site Green=Tags(s)

MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMV
LLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSL
DKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFL
RFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQV
FGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSES
SILTAQEEMTGMNDLGERQSENYPNKEDVGNKSA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 43.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001287
Locus ID 1238
UniProt ID O00590
Cytogenetics 3p22.1
RefSeq Size 2978
RefSeq ORF 1152
Synonyms CCBP2; CCR9; CCR10; CMKBR9; D6; hD6
Summary This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. provided by RefSeq, Jul 2008
Protein Categories Chemokines, GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
FAQs
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SDS
SKU Description Size
PH302459 CCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001287) 10 ug
LC400518 Lyophilized ACKR2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
LY400518 Transient overexpression lysate of chemokine binding protein 2 (CCBP2) (as WB positive control) 100 ug

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