CD27 Antibody
Referência OAEE00765
Tamanho : 100tests(T100)
Marca : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for CD27 Antibody |
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| Predicted Species Reactivity | Human |
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| Product Format | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | LT27 |
| Isotype | IgG2a |
| Host | Mouse |
| Conjugation | APC |
| Application | FC |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Human peripheral blood lymphocytes |
| Purification | Purified by size-exclusion chromatography |
| Concentration | 10 ul / test |
| Specificity | The antibody LT27 reacts with CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells. HLDA V; WS Code T T-CD27.01 |
| Formulation | APC |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. |
| Reference | Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995). Yun LW, Decarlo AA, Hunter N: Blockade of protease-activated receptors on T cells correlates with alteredproteolysis of CD27 by gingipains of Porphyromonas gingivalis. Clin Exp Immunol. 2007 Nov;150(2):217-29. Kara IO, Sahin B, Gunesacar R: Expression of soluble CD27 and interleukins-8 and -10 in B-cell chroniclymphocytic leukemia: correlation with disease stage and prognosis. Adv Ther. 2007 Jan-Feb;24(1):29-40. Molica S, Vitelli G, Levato D, Crispino G, Dell'Olio M, Dattilo A, Matera R, Gandolfo GM, Musto P. CD27 in B-cell chronic lymphocytic leukemia. Cellular expression, serum release and correlation with other soluble molecules belonging to nerve growth factor receptors (NGFr) superfamily. Haematologica. 1998 May;83(5):398-402. van Oers MH, Pals ST, Evers LM, van der Schoot CE, Koopman G, Bonfrer JM, Hintzen RQ, von dem Borne AE, van Lier RA: Expression and release of CD27 in human B-cell malignancies. Blood. 1993 Dec 1;82(11):3430-6. |
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| Gene Symbol | CD27 |
| Gene Full Name | CD27 molecule |
| Alias Symbols | CD27 antigen, CD27L receptor, S152, S152. LPFS2, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7. |
| NCBI Gene Id | 939 |
| Protein Name | CD27 antigen |
| Description of Target | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
| Uniprot ID | P26842 |
| Protein Accession # | NP_001233.1 |
| Nucleotide Accession # | NM_001242.4 |
