Aristolochic acid C [4849-90-5]

Imprimir

Referência NB-64-61837-25mg

Tamanho : 25mg

Contactar o distribuidor local :

Telefone : +1 850 650 7790

Marca : Neo Biotech

Solicitar mais informações

Contactar o distribuidor local :

Telefone : +1 850 650 7790

Aristolochic acid C

Catalog No. TN1064 Copy Product Info

Purity: 99.8%

Aristolochic acid C, a derivative of Aristolochic acid, acts as a phospholipase A2 inhibitor.

Aristolochic acid C

Copy Product Info

Aristolochic acid C, a derivative of Aristolochic acid, acts as a phospholipase A2 inhibitor.

Cas No. 4849-90-5

Customer service consultation

Batch Information

Select Batch

Purity:99.8%

Appearance:Solid

Color:Orange

Resource Download

COA LCMS

Product Introduction

Aristolochic acid C AI Summary

Aristolochic acid C exhibits a bioactivity of inhibiting CDK2 with an IC50 value of 30,000 nM. Additionally, it shows anti-inflammatory activity in human neutrophils by inhibiting fMLP/CB-induced superoxide anion generation and elastase release after 5 minutes, with an IC50 value greater than 10.0 µg/mL, indicating moderate to weak inhibitory activity at this concentration..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Aristolochic acid C, a derivative of Aristolochic acid, acts as a phospholipase A2 inhibitor.

Chemical Properties

Molecular Weight	327.25
Formula	C₁₆H₉NO₇
Cas No.	4849-90-5
Smiles	OC(=O)c1cc2OCOc2c2c3cc(O)ccc3cc([N+]([O-])=O)c12
Relative Density.	1.707 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (381.97 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (12.22 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0558 mL	15.2788 mL	30.5577 mL	152.7884 mL
5 mM	0.6112 mL	3.0558 mL	6.1115 mL	30.5577 mL
10 mM	0.3056 mL	1.5279 mL	3.0558 mL	15.2788 mL
20 mM	0.1528 mL	0.7639 mL	1.5279 mL	7.6394 mL
50 mM	0.0611 mL	0.3056 mL	0.6112 mL	3.0558 mL
100 mM	0.0306 mL	0.1528 mL	0.3056 mL	1.5279 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.