Anti-RUNX2 Antibody (4W937)
Referência NB-64-119009-100uL
Tamanho : 100uL
Marca : Neo Biotech
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Telefone : +1 850 650 7790
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Anti-RUNX2 Antibody (4W937)
(Synonyms: SL3/AKV core binding factor alpha A subunit, SL3 3 enhancer factor 1 alpha A subunit, RUNX 2, Runt-related Transcription Factor 2, Runt related transcription factor 2, Runt domain, Polyomavirus enhancer binding protein 2 alpha A subunit, PEBP2-alpha A, PEBP2aA1, PEBP2A2, PEBP2A1, PEBP2 alpha A, PEA2aA, PEA2 alpha A, OTTHUMP00000016533, Osteoblast specific transcription factor 2, OSF2, OSF 2, Oncogene AML 3, MGC120023, Core binding factor subunit alpha 1, Core binding factor runt domain alpha subunit 1, Core binding factor, Cleidocranial dysplasia 1, CLCD, CCD1, CCD, CBFA1, CBF alpha 1, AML3) Copy Product InfoSynonyms: SL3/AKV core binding factor alpha A subunit, SL3 3 enhancer factor 1 alpha A subunit, RUNX 2, Runt-related Transcription Factor 2, Runt related transcription factor 2, Runt domain, Polyomavirus enhancer binding protein 2 alpha A subunit, PEBP2-alpha A, PEBP2aA1, PEBP2A2, PEBP2A1, PEBP2 alpha A, PEA2aA, PEA2 alpha A, OTTHUMP00000016533, Osteoblast specific transcription factor 2, OSF2, OSF 2, Oncogene AML 3, MGC120023, Core binding factor subunit alpha 1, Core binding factor runt domain alpha subunit 1, Core binding factor, Cleidocranial dysplasia 1, CLCD, CCD1, CCD, CBFA1, CBF alpha 1, AML3
Catalog No. TMAC-03664 Copy Product Info
Anti-RUNX2 Antibody (4W937) is a Rabbit antibody targeting RUNX2. Anti-RUNX2 Antibody (4W937) can be used in ICC/IF,IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-RUNX2 Antibody (4W937) is a Rabbit antibody targeting RUNX2. Anti-RUNX2 Antibody (4W937) can be used in ICC/IF,IHC,WB. |
| Synonyms | SL3/AKV core binding factor alpha A subunit, SL3 3 enhancer factor 1 alpha A subunit, RUNX 2, Runt-related Transcription Factor 2, Runt related transcription factor 2, Runt domain, Polyomavirus enhancer binding protein 2 alpha A subunit, PEBP2-alpha A, PEBP2aA1, PEBP2A2, PEBP2A1, PEBP2 alpha A, PEA2aA, PEA2 alpha A, OTTHUMP00000016533, Osteoblast specific transcription factor 2, OSF2, OSF 2, Oncogene AML 3, MGC120023, Core binding factor subunit alpha 1, Core binding factor runt domain alpha subunit 1, Core binding factor, Cleidocranial dysplasia 1, CLCD, CCD1, CCD, CBFA1, CBF alpha 1, AML3 |
| Ig Type | IgG |
| Clone | 4W937 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-RUNX2 antibody. Counter stained with hematoxylin. 2. ICC staining RUNX2 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.  , |
| Application | ICC/IF IHC WB |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2αB, CBFA2), RUNX2 (also designated AML-3, PEBP2αA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPαC, CBFA3). RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID | Q13950 |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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