Amyloid β-Peptide (1-42) human,TFA [107761-42-2]

Biological Activity

Amyloid β-Peptide (1-42) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.

Product Citations

• 

  Cell Rep. 2025 Oct 28;44(10):116428.

  DEAD-box helicase DDX24 is essential for endothelial mitochondrial function to maintain the blood-brain barrier
  Amyloid β-Peptide (1-42) human,TFA purchased from AbMole

• 

  Basic and Clinical Medicine. 2024 Jul 29;44 (08).

  Nervous protection provided by notoginsenoside Rg1 in rat model with Alzheimer's disease
  Amyloid β-Peptide (1-42) human,TFA purchased from AbMole

Chemical Information

Molecular Weight	4514.04
Formula	C203H311N55O60S
CAS Number	107761-42-2
Solubility (25°C)	DMSO 30 mg/mL
Storage	-20°C, dry, sealed

References

[1] Olayemi Joseph Olajide, et al. Amyloid-β (1-42) peptide induces rapid NMDA receptor-dependent alterations at glutamatergic synapses in the entorhinal cortex

[2] Eun-Jeong Yang, et al. Phloroglucinol attenuates oligomeric amyloid beta peptide 1-42-induced astrocytic activation by reducing oxidative stress

[3] Marcia A LeVatte, et al. Preparation and characterization of a highly soluble Aβ 1-42 peptide variant

[4] D Allan Butterfield, et al. Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer's Disease

[5] Roberta Facchinetti, et al. An Animal Model of Alzheimer Disease Based on the Intrahippocampal Injection of Amyloid β-Peptide (1-42)

[6] W Blaine Stine, et al. Methods Mol Biol. Preparing synthetic Aβ in different aggregation states