4 Hydroxynonenal Polyclonal Antibody, APC-Cy7 Conjugated
Referência bs-6313R-APC-Cy7
Tamanho : 100uL
Marca : Bioss
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Applications
Reactivity
| Overview | |
| Catalog # | bs-6313R-APC-Cy7 |
| Product Name | 4 Hydroxynonenal Polyclonal Antibody, APC-Cy7 Conjugated |
| Applications | WB, IF(IHC-P) |
| Reactivity | Others |
| Specifications | |
| Conjugation | APC-Cy7 |
| Host | Rabbit |
| Source | KLH-conjugated 4-hydroxynonenal |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Cytoplasm |
| Synonyms | 4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; 4 HNE; 4HNE; 4-HNE; E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA. |
| Background | Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |