- Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of VEGFA.
Immunogen
A synthetic peptide corresponding to amino acids 150-250 of human VEGFA.
Host
Rabbit
Reactivity
Bovine, Chicken, Dog, Guinea pig, Human, Mouse, Pig, Rat
Specificity
This is specific to VEGFA. This antibody is useful for Western blot analysis, where a band is seen at ~42 KDa with a chimera transfected lysate, representing the homodimer VEGFA. Another faint band is seen at ~21 KDa, representing the monodomer form of VEGFA.
Form
Liquid
Conjugation
DyLight 488
Recommend Usage
Western Blot (1 ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM sodium borate
Storage Instruction
Store at 4°C. Do not freeze.
- Applications
Western Blot
- Gene Info — VEGFA
Entrez GeneID
7422Protein Accession#
P15692Gene Name
VEGFA
Gene Alias
MGC70609, VEGF, VEGF-A, VPF
Gene Description
vascular endothelial growth factor A
Gene Ontology
HyperlinkGene Summary
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq
Other Designations
vascular endothelial growth factor isoform VEGF165|vascular permeability factor
- Interactomes
- Pathways
- Diseases
VEGFA polyclonal antibody (DyLight 488)
Referencia PAB15095
embalaje : 100uL
Marca : Abnova
Contact local distributor :
Teléfono : +1 850 650 7790