Trk C (phospho Tyr516) Polyclonal Antibody
Referencia AP67732
embalaje : 100ul
Marca : Abcepta
Contact local distributor :
Teléfono : +1 850 650 7790
Trk C (phospho Tyr516) Polyclonal Antibody
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Western Blot analysis of HELA cells using Phospho-Trk C (Y516) Polyclonal Antibody
Western Blot analysis of HELA cells using Phospho-Trk C (Y516) Polyclonal Antibody
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q16288 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 94428 Da |
| Gene ID | 4916 |
|---|---|
| Other Names | NTRK3; TRKC; NT-3 growth factor receptor; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. IHC-P~~N/A |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NTRK3 |
|---|---|
| Synonyms | TRKC |
| Function | Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain |
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