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Result Data
Note

Result Data

Result Data

Inhibition of SIRT3 by Nicotinamide (IC50= 200 uM).

  • Specifications

    Product Description

    SIRT3 Direct Fluorescent Screening Assay Kit provides a fluorescence-based method for screening SIRT3 inhibitors or activators.

    Regulation Status

    For research use only (RUO)

    Storage Instruction

    Store the kit at -80°C.

    Note

    Result Data

  • Applications

    Functional Study

  • Gene Info — SIRT3

    Entrez GeneID

    23410

    Gene Name

    SIRT3

    Gene Alias

    SIR2L3

    Gene Description

    sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)

    Omim ID

    604481

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq

    Other Designations

    mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase|silent mating type information regulation 2, S.cerevisiae, homolog 3|sir2-like 3|sirtuin 3|sirtuin type 3

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