Polyethylene glycol 12-hydroxystearate [61909-81-7]
Referencia NB-64-09415-5g
embalaje : 5g
Marca : Neo Biotech
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Teléfono : +1 850 650 7790
Polyethylene glycol 12-hydroxystearate (Synonyms: Solutol HS-15)
Catalog No. T19562 Copy Product Info
Purity: 98%
Polyethylene glycol 12-hydroxystearate (Solutol HS-15) is a permeability enhancer.
Polyethylene glycol 12-hydroxystearate
Copy Product InfoSynonyms Solutol HS-15
Polyethylene glycol 12-hydroxystearate (Solutol HS-15) is a permeability enhancer.
Cas No. 61909-81-7
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Polyethylene glycol 12-hydroxystearate (Solutol HS-15) is a permeability enhancer. |
| In vitro | Polyethylene glycol 12-hydroxystearate promotes the apical-to-basolateral translocation of a model protein (insulin) across Calu-3 monolayers when applied at 37°C. Furthermore there is no statistically significant increase in insulin permeability in the presence of Polyethylene glycol 12-hydroxystearate, relative to the respective control, at 4°C. Polyethylene glycol 12-hydroxystearate treated cells show a statistically significant increase in permeability towards lower molecular weight permeants (5 to 22 kDa) and an absence of a statistically significant increase in permeability of proteins with larger molecular weight, namely albumin and IgG (P>0.05 relative to control). |
| Synonyms | Solutol HS-15 |
| Formula | (C2H4O)nC18H36O3 |
| Cas No. | 61909-81-7 |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | DMSO: 262.00 mg/mL  Ethanol: 100.00 mg/mL, Sonication is recommended. H2O: 25.00 mg/mL, Sonication is recommended. |