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> Mouse Anti-TBX19 Monoclonal Antibody [Clone:CL6251]

Mouse Anti-TBX19 Monoclonal Antibody [Clone:CL6251]

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Referencia AMAb91409

embalaje : 100ul

Marca : Atlas Antibodies

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Teléfono : +1 850 650 7790

AMAb91409
T-box 19

Anti-TBX19 Antibody

Monoclonal Antibody against HUMAN TBX19

1.0 mg/ml
Anti-TBX19 Antibody
Anti-TBX19 Antibody
Anti-TBX19 Antibody
Anti-TBX19 Antibody
Anti-TBX19 Antibody
info@quimigen.pt

Immunohistochemical staining of human pituitary gland shows strong nuclear immunoreactivity in a subset of cells in the adenohypophysis.

Product Features

This transcriptional regulator plays a crucial role in developmental processes by modulating gene expression. It is known to activate the expression of the POMC gene while simultaneously repressing the promoters of the alpha glycoprotein subunit and thyroid-stimulating hormone beta. Understanding its function can provide insights into developmental biology and endocrine regulation. 

Product details

  • Target protein: T-box 19
  • Target gene: TBX19
  • Verified species reactivity: Human
  • Interspecies information: Highest antigen sequence indentity to the following orthologs: MOUSE - ENSMUSG00000026572 (82%)RAT - ENSRNOG00000025634 (32%)
  • Clonality: Monoclonal
  • Clone ID: CL6251
  • Isotype: IgG1
  • Host: Mouse
  • Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
    Material Safety Data Sheet
  • Purification method: Protein A purified
  • Notes: The antibody solution should be gently mixed before use. Optimal concentrations and conditions for each application should be determined by the user.

Current lot

  • Unit size: 100µl
  • Current lot: MAB-04339
  • Concentration: 1.0 mg/ml

Applications

  • Immunohistochemistry (IHC) recommended conditions
    • Dilution: 1:1000 - 1:2500
    • Retrieval method: HIER pH6

Validation

  • Immunohistochemistry (IHC) 

Target information

  • Protein name: T-box 19
  • Gene name: TBX19
  • Alternative gene names: dj747L4.1, TPIT, T-PIT, 
  • Ensembl: 
  • Entrez: 
  • UniProt: 

Shipping and storage

  • Shipping: Normally shipped at ambient temperatureStorage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References (12)

  • Dottermusch M, Ryba A, Gocke A, Rafiq T, Soltwedel C, Lempertz T, Haberbosch L, Schmid S, Perez-Rivas LG, Theodoropoulou M, Uksul N, Knappe UJ, Schweizer L, Saeger W, Matschke J, Bujko M, Schüller U, Glatzel M, Flitsch J, Ricklefs FL, Neumann JENat Commun , 2026 Aug 4; 17(1). Epub 2026 Aug 42026 Aug 4
  • Carbonara F, Gianno F, Feola T, Mancinelli F, De Alcubierre D, Moroni M, Lucantonio E, Arcella A, Di Pardo A, Morace R, Isidori AM, Gambardella S, Esposito V, Jaffrain-Rea MLEndocr Pathol , 2026 Jan 2; 37(1):2. Epub 2026 Jan 22026 Jan 2

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