Losartan potassium ['124750-99-8]
Referencia M2258-100mg
embalaje : 100mg
Marca : AbMole Bioscience
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Teléfono : +1 850 650 7790
All AbMole products are for research use only, cannot be used for human consumption.
DuP-753 potassium
Quality Control & Documentation
Biological Activity
Losartan potassium is a selective non-peptide angiotensin AT1 receptor antagonist. Losartan potassium inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA2 = 8.27). Losartan potassium is an angiotensin II receptor antagonist drug.
Chemical Information
| Molecular Weight | 462.01 |
| Formula | C22H23ClKN6O |
| CAS Number | 124750-99-8 |
| Solubility (25°C) | DMSO 78 mg/mL Water 39 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Yongjun Lou, et al. Quantification of Losartan Potassium Polymorphs Using Powder X-Ray Diffraction
[2] Abdul-Rahman A Al-Majed, et al. Losartan: Comprehensive Profile
[3] Domenic A Sica, et al. Clinical pharmacokinetics of losartan
[4] L M Burrell. A risk-benefit assessment of losartan potassium in the treatment of hypertension
[5] K L Goa, et al. Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension