Human total cholesterol (TC) ELISA Kit
Referencia MBS269998-96
embalaje : 96-Strip-Wells
Marca : MyBiosource
Contact local distributor :
Teléfono : +1 850 650 7790
Total Cholesterol (TC) ELISA Kit for Human
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS269998Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Human TC monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and… More details
Product Overview
Online Datasheet in PDFProduct Name
total cholesterol (TC), ELISA Kit
Full Product Name
Human total cholesterol (TC) ELISA Kit
Product Gene Name
TC elisa kit
Species Reactivity
Human
Assay Type
Sandwich
Detection Range
20 mmol/L-0.312 mmol/L
Sensitivity
Up to 0.06 mmol/L
Specificity
No cross-reaction with other factors.
Preparation and Storage
Store all reagents at 2-8 degree C.
Inter-assay Precision
<= 12%
Intra-assay Precision
<= 8%
Molecular Weight
44,421 Da
OMIM
613441
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of TC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for TC purchase
MBS269998 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the total cholesterol (TC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TC. The ELISA analytical biochemical technique of the MBS269998 kit is based on TC antibody-TC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for TC. It may not necessarily be applicable to this product.
NCBI Official Full Name
transcobalamin-2 isoform 2
NCBI Official Synonym Full Names
transcobalamin II
NCBI Official Symbol
TCN2
NCBI Official Synonym Symbols
II; TC; TC2; TC-2; TCII; TC II; D22S676; D22S750
UniProt Protein Name
Transcobalamin-2
UniProt Synonym Protein Names
Transcobalamin II; TC II; TCII
UniProt Gene Name
TCN2
UniProt Synonym Gene Names
TC2; TC-2; TC II; TCII
UniProt Entry Name
TCO2_HUMAN
NCBI Protein Information
transcobalamin-2; macrocytic anemia; vitamin B12-binding protein 2; transcobalamin II; macrocytic anemia
NCBI Summary for TC
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Show more UniProt Comments for TC
TCN2: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. Defects in TCN2 are the cause of transcobalamin II deficiency (TCN2 deficiency). This results in various forms of anemia. Belongs to the eukaryotic cobalamin transport proteins family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: extracellular space; lysosomal lumen; extracellular region; endosome
Molecular Function: metal ion binding; cobalamin binding
Biological Process: vitamin metabolic process; cobalamin metabolic process; cobalamin transport; cobalt ion transport; water-soluble vitamin metabolic process
Disease: Transcobalamin Ii Deficiency
Show more Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: extracellular space; lysosomal lumen; extracellular region; endosome
Molecular Function: metal ion binding; cobalamin binding
Biological Process: vitamin metabolic process; cobalamin metabolic process; cobalamin transport; cobalt ion transport; water-soluble vitamin metabolic process
Disease: Transcobalamin Ii Deficiency
Research Articles on TC
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with TC elisa kit
| Reference Product | PubMed Publications |
|---|---|
| MTR elisa kit | >20 publications with TC and MTR |
| DHFR elisa kit | >4 publications with TC and DHFR |
| CD320 elisa kit | >4 publications with TC and CD320 |
| CBL elisa kit | >3 publications with TC and CBL |
| MUT elisa kit | >2 publications with TC and MUT |
| AK1 elisa kit | >1 publications with TC and AK1 |
Pathways associated with TC elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway antibodies | Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway Diagram |
| Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies | Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram |
| Defective BTD Causes Biotidinase Deficiency Pathway antibodies | Defective BTD Causes Biotidinase Deficiency Pathway Diagram |
| Defective CD320 Causes Methylmalonic Aciduria Pathway antibodies | Defective CD320 Causes Methylmalonic Aciduria Pathway Diagram |
| Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies | Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram |
| Defective GIF Causes Intrinsic Factor Deficiency Pathway antibodies | Defective GIF Causes Intrinsic Factor Deficiency Pathway Diagram |
| Defective HLCS Causes Multiple Carboxylase Deficiency Pathway antibodies | Defective HLCS Causes Multiple Carboxylase Deficiency Pathway Diagram |
| Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway antibodies | Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway Diagram |
| Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway antibodies | Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway Diagram |
| Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway antibodies | Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway Diagram |
Diseases associated with TC elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| TRANSCOBALAMIN II DEFICIENCY Antibodies | >12 publications with TC and TRANSCOBALAMIN II DEFICIENCY |
| Nervous System Diseases Antibodies | >9 publications with TC and Nervous System Diseases |
| Brain Diseases Antibodies | >5 publications with TC and Brain Diseases |
| Vascular Diseases Antibodies | >5 publications with TC and Vascular Diseases |
| Anemia Antibodies | >5 publications with TC and Anemia |
| Anemia, Megaloblastic Antibodies | >5 publications with TC and Anemia, Megaloblastic |
| Cleft Lip Antibodies | >4 publications with TC and Cleft Lip |
| Colorectal Neoplasms Antibodies | >3 publications with TC and Colorectal Neoplasms |
| Kidney Diseases Antibodies | >2 publications with TC and Kidney Diseases |
| Heart Diseases Antibodies | >2 publications with TC and Heart Diseases |
Organs/Tissues associated with TC elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >28 publications with TC and Blood |
| Heart Antibodies | >4 publications with TC and Heart |
| Kidney Antibodies | >3 publications with TC and Kidney |
| Brain Antibodies | >3 publications with TC and Brain |
| Bone Marrow Antibodies | >2 publications with TC and Bone Marrow |
| Muscle Antibodies | >1 publications with TC and Muscle |
| Prostate Antibodies | >1 publications with TC and Prostate |
| Bladder Antibodies | >1 publications with TC and Bladder |
| Intestine Antibodies | >1 publications with TC and Intestine |
| Vascular Antibodies | >1 publications with TC and Vascular |
Usted podría estar interesado también en los siguientes productos:
Referencia
Descripción
Cond.
Precio Sin IVA
