Human EGFR Antibody : PE (Phospho-Tyr1068)
Referencia OAAQ00077-10tests
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Human EGFR Antibody : PE (Phospho-Tyr1068)
Human EGFR Antibody : PE (Phospho-Tyr1068) (OAAQ00077)
| Datasheets/Manuals | Printable datasheet for OAAQ00077 |
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| Tested Species Reactivity | Human, Mouse, Rat |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | EGFRY1068-E5 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | PE: Phycoerythrin |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human phospho EGFR. |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Tyr1068 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | (1) Herbst RS (2004). "Review of epidermal growth factor receptor biology". International Journal of Radiation Oncology, Biology, Physics. 59 (2 Suppl): 21-6. (2) Zhang H, Berezov A, Wang Q, Zhang G, Drebin J, Murali R, Greene MI (August 2007). "ErbB receptors: from oncogenes to targeted cancer treatment". The Journal of Clinical Investigation. 117 (8): 2051-8. |
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| Gene Symbol | EGFR |
| Gene Full Name | epidermal growth factor receptor |
| Alias Symbols | ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2 |
| NCBI Gene Id | 1956 |
| Protein Name | epidermal growth factor receptor |
| Description of Target | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. |
| Uniprot ID | P00533 |
| Protein Accession # | NP_005219.2 |
| Nucleotide Accession # | NM_005228.4 |
