Hepatitis B Surface Antigen / HBsAg (ayw) Protein
Referencia BIN061
embalaje : 500ug
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Hepatitis B Surface Antigen / HBsAg (ayw) Protein
SKU
BIN061
Hepatitis B Surface Antigen / HBsAg (ayw) recombinant protein, 0.5 mg
| Product Data | |
| Expression Host | S. cerevisiae |
|---|---|
| Concentration | lot specific |
| Purity | >98% pure by SDS-PAGE). Purification is conducted from broken yeast cells by the following scheme: Clarification, Microfiltration, Ultrafiltration, Adsorption Chromatography, Ion-exchange chromatography, Ultracentrifugation and Sterile Filtration. Product is sterile filtered. |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Liquid (sterile filtered) purified protein. Buffer System: 0.05M Phosphate, 0.2M NaCl, pH 7.2 without preservatives. |
| Preparation | Liquid (sterile filtered) purified protein. |
| Recommended Dilution | Tested in ELISA with anti-HBsAg antibodies. |
| Protein Description | Recombinant Hepatitis B Surface Antigen (HBsAg), (ayw) (S region). Recombinant HBsAg is a 24 kDa protein. Genotype B. Does not contain a fusion partner. |
| Storage | Store the antigen at 2-8°C. |
| Stability | Shelf life: six months from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| Synonyms | HBV surface antigen, Hepatitis B Virus |
| Summary | Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. |
| Protein Families | Tested in ELISA with anti-HBsAg antibodies. |
| FAQs |
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| SDS |
| Recombinant Protein Resources |
Citations
Immunogenicity of Leishmania-derived hepatitis B small surface antigen particles exposing highly conserved E2 epitope of hepatitis C virus
Czarnota, Tyborowska, Peszyńska-Sularz et al
Microb Cell Fact (2016) 15, 62 DOI: 10.1186/s12934-016-0460-4
Czarnota, Tyborowska, Peszyńska-Sularz et al
Microb Cell Fact (2016) 15, 62 DOI: 10.1186/s12934-016-0460-4
Cited by 29
AI Summary: OriGene products, specifically the Myc-DDK monoclonal antibody (Cat# TA50011-100) and anti-DDK (FLAG) antibody (Cat# TA50011), were used in this study to detect and confirm the expression of the chimeric sHBsAg proteins in immunoblot and immunogold staining experiments.
Showing 1-1 of 1 papers.
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