GET4 Antibody - C-terminal region - FITC
Referencia ARP61197_P050-FITC
embalaje : 100ul
Marca : Aviva Systems Biology
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GET4 Antibody - C-terminal region : FITC (ARP61197_P050-FITC)
| Datasheets/Manuals | Printable datasheet for anti-GET4 (ARP61197_P050-FITC) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Guinea Pig, Yeast |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | FITC: Fluorescein Isothiocyanate |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C-terminal region of Human GET4 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Guinea Pig: 77%; Human: 100%; Mouse: 77%; Rat: 77%; Yeast: 77% |
| Peptide Sequence | Synthetic peptide located within the following region: DRIGQLFFGVPPKQTSSYGGLLGNLLTSLMGSSEQEDGEESPSDGSPIEL |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-GET4 (ARP61197_P050-FITC) antibody is Catalog # AAP61197 |
| Gene Symbol | GET4 |
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| Gene Full Name | golgi to ER traffic protein 4 homolog (S. cerevisiae) |
| Alias Symbols | CEE, TRC35, CGI-20, C7orf20 |
| NCBI Gene Id | 51608 |
| Protein Name | Golgi to ER traffic protein 4 homolog |
| Description of Target | GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting. |
| Uniprot ID | Q7L5D6-2 |
| Protein Size (# AA) | 274 |
| Molecular Weight | 30kDa |
| Protein Interactions | HUWE1; PRKAB2; FAF1; VAPB; SGTA; UBC; RABEP2; LSM8; MTA2; CSTF2; FAF2; BAG6; UBL4A; VCP; EXOC2; SEC61B; TRA; AMFR; KEAP1; TMEM256; KIAA1377; ATP5H; KIFC2; EEF1G; UBAC2; SNCAIP; PLK1; PRKCSH; KAT5; TTR; PTMS; SOD2; CDKN1A; CAPNS1; WRAP73; |
