FOXO1A antibody - N-terminal region
Referencia ARP38094_T100
embalaje : 100ul
Marca : Aviva Systems Biology
Contact local distributor :
Teléfono : +1 850 650 7790
FOXO1A Antibody - N-terminal region (ARP38094_T100)
| Datasheets/Manuals | Printable datasheet for anti-FOXO1 (ARP38094_T100) antibody |
|---|
| Publications | Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway Ambient temperature influences aging in an annual fish (Nothobranchius rachovii) |
|---|---|
| Tested Species Reactivity | Human |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Pig, Yeast |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A |
| Purification | Protein A purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 92%; Dog: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rat: 85%; Yeast: 85% |
| Peptide Sequence | Synthetic peptide located within the following region: MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAA |
| Concentration | 1.0 mg/ml |
| Blocking Peptide | For anti-FOXO1 (ARP38094_T100) antibody is Catalog # AAP38094 (Previous Catalog # AAPP20268) |
| Reference | Okamoto,H., et al., (2006) J. Clin. Invest. 116 (3), 775-782 |
|---|---|
| Gene Symbol | FOXO1 |
| Gene Full Name | Forkhead box O1 |
| Alias Symbols | FKH1, FKHR, FOXO1A |
| NCBI Gene Id | 2308 |
| Protein Name | Forkhead box protein O1 |
| Description of Target | FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma. |
| Uniprot ID | Q12778 |
| Protein Accession # | NP_002006 |
| Nucleotide Accession # | NM_002015 |
| Protein Size (# AA) | 655 |
| Molecular Weight | 70kDa |
| Protein Interactions | EP300; AKT1; MST1; SIRT1; FHL2; ATG7; IRF3; FSHR; ESR1; Ubc; TXNRD1; RARA; MDM2; NLK; SKP2; SIRT2; STUB1; CREBBP; PML; LRPPRC; HOXA11; HNF4A; PARP1; DYRK1A; THRB; CSNK1G1; YWHAG; GSK3B; SMAD3; PAK1; PPARG; YWHAZ; SMAD4; AR; G6PC; SRC; CEBPB; FOXG1; HOXA10 |
