apoptosis regulator Bcl-X, bcl-2-like protein 1, Bcl-X, BCL-XL/S, BCL2L, BCLX, PPP1R52, protein phosphatase 1, regulatory subunit 52.
NCBI Gene Id
598
Protein Name
Bcl-2-like protein 1
Description of Target
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.