Bcl-2 (P65) polyclonal antibody

Referencia BS1511-100ul

embalaje : 100ul

Marca : Bioworld Technology

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Teléfono : +1 850 650 7790

Product NameBcl-2 (P65) polyclonal antibody
Catalog No.BS1511
Swiss-ProtP10415
Host Rabbit
ReactivityHuman,Mouse,Rat
ApplicationsWB IHC IF
Application_allWB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
BiowMW~ 26 kDa
Alternative NameApoptosis regulator Bcl-2; Bcl 2; BCL2
Purification&PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ConjugateUnconjugated
ModificationUnmodification
Product Name :
Bcl-2 (P65) polyclonal antibody
Background :
Bcl-2 is one among many key regulators of apoptosis which are essential for proper development, tissue homeostasis and protection against foreign pathogens. Human Bcl-2 is a 26 kDa, membraneassociated, anti-apoptotic oncoprotein that can promote cell survival through protein-protein interactions with other Bcl-2 related family members, such as the death suppressors Bcl-xL, Mcl-1, Bcl-w and A1, or the death agonists Bax, Bak, Bik, Bad and BID. The anti-apoptotic function of Bcl-2 can also be regulated through proteolytic processing and phosphorylation. Bcl-2 may promote cell survival by interfering with the activation of the cytochrome c/Apaf-1 pathway through stabilization of the mitochondrial membrane.
Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
Bcl-2 (P65) polyclonal antibody detects endogenous levels of Bcl-2 protein.
Immunogen :
Synthetic peptide, corresponding to amino acids 31-80 of Human Bcl-2.
Conjugate :
Unconjugated
Modification :
Unmodification