AREB6 (ZEB1) Mouse Monoclonal Antibody [Clone ID: OTI3G6]
Referencia TA802298
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AREB6 (ZEB1) Mouse Monoclonal Antibody [Clone ID: OTI3G6]
SKU
TA802298
ZEB1 mouse monoclonal antibody,clone OTI3G6
| Product Data | |
| Clone Name | OTI3G6 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-350 of human ZEB1 (NP_110378) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 123.9 kDa |
| Gene Name | zinc finger E-box binding homeobox 1 |
| Database Link | |
| Background | This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Mar 2010 |
| Synonyms | AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A |
| Note | This ZEB1 antibody (TA802298) does not cross-react with ZEB2 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Nervous system Diseases, Transciption Factors |
| Protein Families | Transcription Factors |
| Product Manuals |
| FAQs |
|
| SDS |
| Antibody Resources |
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| SKU | Description | Size | ||
|---|---|---|---|---|
| CF802298 | Carrier-free (BSA/glycerol-free) ZEB1 mouse monoclonal antibody,clone OTI3G6 | 100 ug | | |
| TA802298AM | ZEB1 mouse monoclonal antibody,clone 3G6, Biotinylated | 100 ul | | |
| TA802298BM | ZEB1 mouse monoclonal antibody,clone 3G6, HRP conjugated | 100 ul | | |
| TA802298S | ZEB1 mouse monoclonal antibody,clone OTI3G6 | 30 ul | | |
Citations
Hypoxic stress promotes astrocyte infiltration-like growth via HIF-1α/GDNF/LOXL2 axis
Li, Xi, Zhang et al
Biochim Biophys Acta Mol Basis Dis (2025)
Li, Xi, Zhang et al
Biochim Biophys Acta Mol Basis Dis (2025)
Cited by 4
AI Summary: In this study, OriGene’s N-cadherin (TA503933S) and ZEB1 (TA802298S) antibodies were used to assess protein expression changes related to astrocyte migration and epithelial-mesenchymal transition under hypoxic stress.
Snippet: o-CREB (Ser133) (CST, 87G3 and 1B6), CREB (CST, 9197), GFRα1 (Bio-techne, AF560-SP), RET (Abcam, ab134100), E-cadherin (BBI, Shanghai, China, D260656), N-cadherin (Origene, Wuxi, China, TA503933S), ZEB1 (Origene, TA802298S), β-actin (Proteintech, 66009-1-Ig), β-tubulin (Proteintech, 66240-1-Ig), and GAPDH (Proteintech, 60004-1-Ig). …
Pro-tumorigenic role of lnc-ZNF30-3 as a sponge counteracting miR-145-5p in prostate cancer
Le Hars, Castro-Vega, Rajabi et al
Biol Direct (2023) 18 (1), 38 DOI: 10.1186/s13062-023-00393-7
Le Hars, Castro-Vega, Rajabi et al
Biol Direct (2023) 18 (1), 38 DOI: 10.1186/s13062-023-00393-7
Cited by 15
AI Summary: In this study, the ZEB1 antibody (TA802298, OriGene) was used in western blot experiments to assess the protein levels of ZEB1, helping to elucidate the role of lnc-ZNF30-3 in regulating EMT-related transcription factors in prostate cancer.
Snippet: dies (dilution, reference, supplier): Vimentin (1:1000, 9782, Cell Signaling), E-Cadherin (1:1000, 9782, Cell Signaling), TWIST1 (1:1000, sc-15,393, Santa Cruz Biotechnology), ZEB1 (1:1000, TA802298, Origene), AGO2 (1:1000, Sab42000085V, Sigma), β-Actin (1:2000, sc-4778, Santa Cruz Biotechnology) were incubated overnight at 4 °C in PBST with 5% non-fat milk. Then membranes were washed 3 times f
Palmitate-Induced IRE1-XBP1-ZEB Signaling Represses Desmoplakin Expression and Promotes Cancer Cell Migration
Nath, Oak, Chen et al
Mol Cancer Res (2021) 19 (2), 240-248 DOI: 10.1158/1541-7786.MCR-19-0480
Nath, Oak, Chen et al
Mol Cancer Res (2021) 19 (2), 240-248 DOI: 10.1158/1541-7786.MCR-19-0480
AI Summary: In this study, OriGene products including the IRE1 CRISPR/Cas9 knockout plasmid (Cat# KN303279) and IRE1 overexpression plasmid (Cat# RC217768) were used to manipulate IRE1 expression in cancer cells, enabling the authors to demonstrate the role of IRE1 in palmitate-induced signaling that represses desmoplakin and promotes cancer cell migration.
CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells
Rajabi, Liu-Bordes, Pinskaya et al
Oncotarget (2020) 11 (45), 4155-4168 DOI: 10.18632/oncotarget.27806
Rajabi, Liu-Bordes, Pinskaya et al
Oncotarget (2020) 11 (45), 4155-4168 DOI: 10.18632/oncotarget.27806
Cited by 10
Snippet: dilution 1:1000 (ab73287 Abcam) TWIST1 H-81, dilution 1:1000 (sc-15393, Santa Cruz Biotechnology), anti-c-Myc 9E10, dilution 1:1000 (11 667 149 001 ROCHE), anti-ZEB1 OTI3G6, dilution 1:1000 (TA802298 Origene), β-Actin (C4) HRP, dilution 1:2000 (sc-4778 HRP Santa Cruz Biotechnology). Statistical analyses Data are means +/− SD of at least three separate experiments. Statistical significance was
Overexpression of PEAK1 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling
Ding, Tang, Fan et al
Cell Death Dis (2018) 9 (8), 802 DOI: 10.1038/s41419-018-0817-1
Ding, Tang, Fan et al
Cell Death Dis (2018) 9 (8), 802 DOI: 10.1038/s41419-018-0817-1
AI Summary: OriGene products, specifically antibodies against p-JAK1, total JAK1, p-JAK2, total JAK2, Twist1, Twist2, Snail1, Snail2, Zeb1, and Zeb2, were used in this study to detect and analyze key proteins involved in signaling pathways and epithelial-mesenchymal transition related to PEAK1-driven lung cancer progression and metastasis.
Snippet: ge of three independent experiments ± SEM. *P ;The primary antibodies used in our study were as follows: PEAK1 (Santa Cruz Biotechnology, USA);PEAK1/NKF3, E-cadherin, N-cadherin, MMP2, and MMP9 (Abcam, UK);p-AKT, total AKT, p-ERK1/2, total ERK1/2, p-JNK and total JNK (Invitrogen, USA);p-Rac1, total Rac1, p-JAK1, total JAK1, p-JAK2, total JAK2, Twist1" style="font-weight: bold;">Twist1, Twist2" style="font-weight: bold;">Twist2, Snail1, Snail2, Zeb1, and Zeb2 (OriGene, USA);and GAPDH (Immunology Consultants Laboratory, USA). …
Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma
Nath, Li, Roberts et al
Sci Rep (2015) 5, 14752 DOI: 10.1038/srep14752
Nath, Li, Roberts et al
Sci Rep (2015) 5, 14752 DOI: 10.1038/srep14752
Cited by 338
AI Summary: OriGene products, specifically the CD36 cDNA clone (RC211307) and CD36 shRNA (TL314482), were used in this study to manipulate CD36 expression levels in liver cancer cell lines, enabling the authors to demonstrate that CD36-mediated free fatty acid uptake promotes epithelial-mesenchymal transition in hepatocellular carcinoma.
Showing 1-6 of 6 papers.
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