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> Anti-FGFR2 Antibody (1A889)

Anti-FGFR2 Antibody (1A889)

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Anti-FGFR2 Antibody (1A889)

(Synonyms: TK25, TK14, K-SAM, KGFR, JWS, FLJ98662, FGFR2 α (IIIb), FGFR2 α, FGFR2 alpha, FGF R2a, ECT1, CFD1, CEK3, CD332, BFR-1, BEK, BBDS) Copy Product Info

Synonyms: TK25, TK14, K-SAM, KGFR, JWS, FLJ98662, FGFR2 α (IIIb), FGFR2 α, FGFR2 alpha, FGF R2a, ECT1, CFD1, CEK3, CD332, BFR-1, BEK, BBDS

Catalog No. TMAH-00432 Copy Product Info
Anti-FGFR2 Antibody (1A889) is an antibody targeting FGFR2. Anti-FGFR2 Antibody (1A889) can be used in ELISA,IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-FGFR2 Antibody (1A889) is an antibody targeting FGFR2. Anti-FGFR2 Antibody (1A889) can be used in ELISA,IHC,WB.
SynonymsTK25, TK14, K-SAM, KGFR, JWS, FLJ98662, FGFR2 α (IIIb), FGFR2 α, FGFR2 alpha, FGF R2a, ECT1, CFD1, CEK3, CD332, BFR-1, BEK, BBDS
Ig Type
hIgG1
Clone
1A889
Reactivity
Human
Verified Activity
1. Western Blot
-Positive WB detected in:hela whole cell lysate (20µg), HT29 whole cell lysate (20µg)
-All lanes: FGFR2 antibody at 1:1000
-Secondary: Goat polyclonal to human IgG at 1/40000 dilution
-Predicted band size:92.03, 86.13, 76.70, 28.29, 40.61, 79 kDa
-Observed band size:41 kDa
-Exposure time:120s
2. IHC image of TMAH-00432 diluted at 1:100 and staining in paraffin-embedded lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
3. IHC image of TMAH-00432 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB."
Application
ELISA
IHC
WB
Recommended Dose
WB:1:500-1:2000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Golgi apparatus. Cytoplasmic vesicle. Note=Detected on osteoblast plasma membrane lipid rafts. After ligand binding, the activated receptor is rapidly internalized and degraded.; [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=After ligand binding, the activated receptor is rapidly internalized and degraded.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein. Note=After ligand binding, the activated receptor is rapidly internalized and degraded.; [Isoform 8]: Secreted.; [Isoform 13]: Secreted.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundTyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes an...
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human FGFR2 protein
Antigen Species
Human
Gene Name
FGFR2
Gene ID
2263
Uniprot ID
P21802
Biology Area
Neuroscience, Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Keywords

TK-25TK-14TK 25TK 14FLJ-98662FLJ 98662ECT-1ECT 1CFD-1CFD 1CEK-3CEK 3CD-332CD 332BFR1BFR 1
Related Tags: Anti-FGFR2 Antibody (1A889) chemical structure