| Short Description : | NA monoclonal anti-CD3-FITC/CD19-PE for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | OKT3, 4G7 |
| Conjugation: | FITC/PE |
| Concentration: | 5 Mu L/Test |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction: | Store between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Background | This product is a FC antibody cocktail made up of FITC Anti-Human CD3 Antibody [Clone: OKT3] (Mouse IgG2a, k) and PE Anti-Human CD19 Antibody [Clone: 4G7] (Mouse IgG1, k). CD3 is a heterotetrameric protein consisting of a CD3 Gamma, a CD Delta and 2 CD3 Epsilon. It forms complex with TCR. OKT-3 recognize human CD3 Epsilon. Human CD3 is expressed on the surface of T cells and NKT cells. CD19 is a single-chain transmembrane glycoprotein expressed on B cells of all stages except plasma cells. It is a common marker for B cells. CD19 is also expressed in follicular dendritic cells. It forms complex with CD21 and CD84, which forms co-receptor with BCR. It takes part in B cell development, activantion and differentiation. |
Information sourced from Uniprot.org