Trometamol [77-86-1]

Pedido mínimo 3

Referencia NB-64-01123-1mL

embalaje : 1mLx10mM(inDMSO)

Marca : Neo Biotech

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Teléfono : +1 850 650 7790

Trometamol (Synonyms: Tromethamine, Tris)

Catalog No. T0961 Copy Product Info
Purity: 99.88%
Trometamol (Tromethamine) is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins.

Trometamol

Copy Product Info
Synonyms Tromethamine, Tris

Trometamol (Tromethamine) is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins.

Trometamol
Cas No. 77-86-1
Select Batch
Purity:99.88%
Appearance:Solid
Color:White
Contact us for more batch information

Product Introduction

Bioactivity
Description
Trometamol (Tromethamine) is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins.
In vivo
The drug is rapidly eliminated by the kidney; 75% or more appears in the urine after eight hours. Urinary excretion continues over a period of three days. The maximum daily dose is 15 mmol/kg for an adult. In large doses, trometamol may induce respiratory depression and hypoglycemia. [1]
SynonymsTromethamine, Tris
Chemical Properties
Molecular Weight121.14
FormulaC4H11NO3
Cas No.77-86-1
SmilesNC(CO)(CO)CO
Relative Density.1.32. Temperature:20.4 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (495.29 mM), Sonication is recommended.
H2O: 198.1 mM, Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM8.2549 mL41.2746 mL82.5491 mL412.7456 mL
5 mM1.6510 mL8.2549 mL16.5098 mL82.5491 mL
10 mM0.8255 mL4.1275 mL8.2549 mL41.2746 mL
20 mM0.4127 mL2.0637 mL4.1275 mL20.6373 mL
50 mM0.1651 mL0.8255 mL1.6510 mL8.2549 mL
100 mM0.0825 mL0.4127 mL0.8255 mL4.1275 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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