TNF alpha (AP)
Referencia MBS6248365-5x0,1mL
embalaje : 5x0.1mL
Marca : MyBiosource
Alpha (TNF) Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6248365MBS6248365 is an antibody targeting TNF. Also known as TNF alpha (AP). Reactive in Bovine, Sheep. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
TNF alpha, Monoclonal Antibody
Full Product Name
TNF alpha (AP)
Product Gene Name
anti-TNF antibody
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
VPM61
Host
Mouse
Species Reactivity
Bovine, Sheep
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by Protein A Affinity Chromatography
Specificity
Recognizes sheep TNF alpha. Species Crossreactivity: bovine.
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Applications Tested/Suitable for anti-TNF antibody
Immunohistochemistry (IHC), Western Blot (WB)
Product References and Citations for anti-TNF antibody
1. Vilmos, P. et al. (1996) Phylogenetically concerved epitopes of leukocyte antigens. Vet. Immunology and Immunopathology 52:415-426. 2. Green, I.R. et al. (1993) Expression and characterization of bioactive recombinant ovine TNF-alpha: some species specificity in cytotoxic response to TNF. Cytokine 5:213-223.
Other Notes
Small volumes of anti-TNF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TNF. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor
NCBI Official Symbol
TNF
NCBI Official Synonym Symbols
TNF-alpha
UniProt Protein Name
Tumor necrosis factor
UniProt Synonym Protein Names
Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a
Protein Family
Tumor necrosis factor
UniProt Gene Name
TNF
UniProt Synonym Gene Names
TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2
UniProt Entry Name
TNFA_SHEEP
NCBI Protein Information
tumor necrosis factor; TNF-a; cachectin; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2
UniProt Comments for TNF
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-TNF antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adipocytokine Signaling Pathway antibodies | Adipocytokine Signaling Pathway Diagram |
| Adipocytokine Signaling Pathway antibodies | Adipocytokine Signaling Pathway Diagram |
| African Trypanosomiasis Pathway antibodies | African Trypanosomiasis Pathway Diagram |
| African Trypanosomiasis Pathway antibodies | African Trypanosomiasis Pathway Diagram |
| Allograft Rejection Pathway antibodies | Allograft Rejection Pathway Diagram |
| Allograft Rejection Pathway antibodies | Allograft Rejection Pathway Diagram |
| Alzheimer's Disease Pathway antibodies | Alzheimer's Disease Pathway Diagram |
| Alzheimer's Disease Pathway antibodies | Alzheimer's Disease Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
Diseases associated with anti-TNF antibody
| Disease Name | Pubmed Publications |
|---|---|
| Necrosis Antibodies | >90724 publications with TNF and Necrosis |
| Inflammation Antibodies | >32770 publications with TNF and Inflammation |
| Vascular Diseases Antibodies | >7574 publications with TNF and Vascular Diseases |
| Lung Diseases Antibodies | >6751 publications with TNF and Lung Diseases |
| Liver Diseases Antibodies | >5155 publications with TNF and Liver Diseases |
| Insulin Resistance Antibodies | >2518 publications with TNF and Insulin Resistance |
| Fibrosis Antibodies | >2488 publications with TNF and Fibrosis |
| Atherosclerosis Antibodies | >2411 publications with TNF and Atherosclerosis |
| Colitis Antibodies | >2408 publications with TNF and Colitis |
| Pain Antibodies | >2277 publications with TNF and Pain |
Organs/Tissues associated with anti-TNF antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Bone Antibodies | >7578 publications with TNF and Bone |


