TET2 Antibody
Referencia OAEB00839
embalaje : 100ug
Marca : Aviva Systems Biology
Contact local distributor :
Teléfono : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for TET2 Antibody (OAEB00839) |
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| Publications | Ten-eleven translocation 1 dysfunction reduces 5-hydroxymethylcytosine expression levels in gastric cancer cells |
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| Tested Species Reactivity | Human |
| Predicted Species Reactivity | Dog|Human|Mouse |
| Product Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Clonality | Polyclonal |
| Host | Goat |
| Application | ELISA|FC|IHC |
| Reconstitution and Storage | -20°C |
| Immunogen | TET2 |
| Purification | Ammonium Sulfate Precipitated; Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Human, Mouse, Dog |
| Peptide Sequence | C-PHPQSNNDQQREGSF |
| Concentration | 0.5 mg/ml |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_001120680.1; NP_060098.3). |
| Application Info | P-ELISA: Antibody detection limit dilution 1:16000 IHC: In paraffin embedded Human Spleen shows nuclear staining in select splenocytes. Recommended concentration: 2-6 ug/ml. |
| Reference | Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG, Massop M, Stevens-Linders E, van Hoogen P, van Kessel AG, Raymakers RA, Kamping EJ, Verhoef GE, Verburgh E, Hagemeijer A, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH, Acquired mutations in TET2 are common in myelodysplastic syndromes. Nature Gen. 2009 Jul 41 (7): 838-42. PMID: 19483684 |
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| Gene Symbol | Tet2|TET2 |
| Gene Full Name | tet methylcytosine dioxygenase 2 |
| Alias Symbols | Ayu17-44, Ayu17-449, E130014J05Rik, IMD75, KIAA1546, MDS, methylcytosine dioxygenase TET2, mKIAA1546, probable methylcytosine dioxygenase TET2, ten-eleven translocation 2, tet oncogene 2, tet oncogene family member 2. |
| NCBI Gene Id | 214133|54790 |
| Protein Name | methylcytosine dioxygenase TET2 isoform a [Homo sapiens]|methylcytosine dioxygenase TET2 isoform b [Homo sapiens] |
| Uniprot ID | Q6N021 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_001120680.1,NP_060098.3 |
| Molecular Weight | 224; 130 |