Sterigmatocystine [10048-13-2]
Referencia NB-64-07943-10mg
embalaje : 10mg
Marca : Neo Biotech
Sterigmatocystine
Catalog No. T16942 Copy Product Info
Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. |
| In vitro | Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, leading to G2 arrest in GES-1 cells [4]. |
| In vivo | Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) suppresses p21WAF1/CIP1 [3]. |
| Molecular Weight | 324.28 |
| Formula | C18H12O6 |
| Cas No. | 10048-13-2 |
| Smiles | 02[C@]12OC=C[C@@]1(02)c1c(O2)cc(OC)c2c1oc1cccc(O)c1c2=O |
| Relative Density. | 1.51 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |


