SARS-CoV-2 Spike RBD E484K, N501Y (South Africa Variant Beta) Recombinant Protein
Referencia OPSN00006
embalaje : 100ug
Marca : Aviva Systems Biology
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Teléfono : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for OPSN00006 |
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| Predicted Species Reactivity | SARS-CoV-2 |
|---|---|
| Product Format | Liquid. 50 mM Tris-HCL, 1M NaCl, pH 7.5 |
| Host | Sf9 Baculovirus |
| Conjugation | Unconjugated |
| Application | IA, AA, FN |
| Additional Information | Lineage: B.1.351, 20H/501Y.V2 |
| Reconstitution and Storage | Store at -20C |
| Formulation | 50 mM Tris-HCL, 1M NaCl, pH 7.5 |
| Purification | IMAC |
| Concentration | 0.14 mg/mL |
| Purity | 90% |
| Tag | C-Avitag/His |
| Reference | Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa https://doi.org/10.1101/2020.12.21.20248640. Sci Rep. 2021 Apr 28;11(1):9166. doi: 10.1038/s41598-021-88696-5. |
| Gene Symbol | S (S1) |
|---|---|
| Gene Full Name | surface glycoprotein |
| Alias Symbols | spike glycoprotein |
| NCBI Gene Id | 43740568 |
| Protein Name | surface glycoprotein |
| Description of Target | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests. |
| Uniprot ID | P0DTC2 |
| Protein Size (# AA) | AA 319-537, E484K, N501Y (South Africa Variant Beta) |
| Molecular Weight | 30kDa |